Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb)

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Taizhou Zecen Biotech Co.,Ltd.

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Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb)

Name: Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody HBeAb
Brand: Zecen
Price: 1 USD

Wholesale Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb) from china suppliers

Brand Name : Zecen

Model Number : HBeAb

Certification : CE, ISO13485

Place of Origin : China

MOQ : 1

Price : Negotiable

Payment Terms : L/C, D/A, D/P, T/T, Western Union, MoneyGram

Supply Ability : 5000 Set/Sets per Month

Delivery Time : 15 workdays

Packaging Details : Carton package

Name : HBeAb/HBeAg

Analyzer : CLIA series

Luminescent markers : AP(alkaline phosphatase)

Calibration : 2-points

Calibrator : Free

Quality Control : Free

Storage : 2-8°C

Material : Magnetic beads, calibrators, Anti A/B, controls

Validity period : 18 months

Precision : ≤8%

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Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb)

HBeAg and Antibodies

Hepatitis B e antibody is a soluble viral protein. It is found early in the course of acute hepatitis B and disappears soon after ALT peaks. Persistence of HBeAg beyond 3 months after the onset of illness is unusual and may suggest progression to chronic infection.

In patients with chronic hepatitis B, the presence of positive HBeAg usually indicates a high level of viral replication and thus infectivity. HBeAg is positive in the immune tolerant phase and in the early immune clearance phase. HBeAg seroconversion is the disappearance of HBeAg and appearance of hepatitis B e antibody (anti-HBe). Most patients enter the inactive HBsAg carrier state after HBeAg seroconversion (Fig. 30-4). This state is associated with low HBV DNA, normal ALT, and little hepatic necroinflammation. However, some patients continue to have active liver disease and detectable serum HBV DNA. This can be due to either a wild-type virus or the presence of precore stop codon mutation and/or basal core promoter mutations that impair HBeAg secretion.9

HBe-AbAg: when present, especially without HBeAb, suggests increased patient infectivity.

HBeAb-total: when present, suggests less patient infectivity.

I.

HBSAg positive, HBCAb negative*

About 5% (range 0%-17%) of patients with early-stage HBV acute infection (HBCAb rises later)

II.

HBSAg positive, HBCAb positive, HBSAb negative

a.: Most of the clinical symptom stage
b.: Chronic HBV carriers without evidence of liver disease (“asymptomatic carriers”)
c.: Chronic HBV hepatitis (chronic persistent type or chronic active type)

III.

HBSAg negative, HBCAb positive,* HBSAb negative

a.: Late clinical symptom stage or early convalescence stage (core window)
b.: Chronic HBV infection with HBSAg below detection levels with current tests
c.: Old previous HBV infection

IV.

HBSAg negative, HBCAb positive, HBSAb positive

a.: Late convalescence to complete recovery
b.: Old infection

^{Clinical significance
(1) Chronic hepatitis B HBeAb positive accounted for 48.3%, liver cirrhosis was 68.3%, and liver cancer was 80%.
(2) The positive rate of HBeAb increased, indicating that most patients were infected with hepatitis B virus for up to 7-27 years.
(3) HBeAb positive will still be infectious to a certain extent. 20% of babies born to HBeAb-positive pregnant women are infected with hepatitis B virus.}

Test Item	HBeAb
Luminescent Principle	Enzymatic chemiluminescence
Luminescent Markers	AP(alkaline phosphatase)
Specification	100/50 Tests/Kit
Specification	/
Principle	Sandwich method
Component	Magnetic Beads
	Calibrator Low
	Calibrator High
	Anti-A/Anti-B
	Control 1
	Control 2
Accessories Required But Not Provided	Substrate
Accessories Required But Not Provided	Washing solution
Sample material	Serum
Storage	2-8℃

Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb) Images

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